After learning about Sherlock Holmes, Humphrey the classroom hamster follows clues to try and discover why Mrs. Brisbane is gone and Mr. E., a fun but not very educational substitute, is taking her place in Room 26 at Longfellow School.
Angelina and some other mice are preparing for a New Year's Eve ice skating show, but the hockey players keep getting in the way until Angelina gets them involved.
As the power of the island to both heal and destroy comes into sharp focus, the lines between good and evil are blurred and loyalties are challenged when the survivors of the crash become tangled within the lives of the Others.