Prison escapee Richard Kimble is a doctor who has been falsely convicted of killing his wife. He is determined to prove his innocence by leading Lt. Philip Gerard to the one-armed man who committed the crime. Because the compassionate Dr. Kimble has a natural inclination to help people, he always gets involved with strangers in need. Many discover his true identity and he is forced to go on the run.

"Dr. Gregory House still has the most unapologetically prickly bedside manner ever, but his genius for solving the medical mysteries other practitioners can't has earned him the respect of his team. House's unpredictable cases, from killer germs to killer secrets, strain his already tenuous relationship with his co-workers and put his own health at risk."--Container.

Dr. Richard Kimble is accused of murdering his wife. The night before his execution, he escapes. The only chance to prove his innocence is to find the man who killed his wife. Kimble, pursued by Lt. Gerard, risks his life several times when he shows his identity to help other people out of trouble. Included are fifteen episodes from the first half of season four.