When sixteen-year-old Jayd Jackson returns to South Bay High, she discovers that her former best friend is out to get her and her ex-boyfriend's new girlfriend wants to fight, which forces Jayd to turn to Mama and her bag of tricks for help.

Cammi's mother is a glamorous telenovela actress in Mexico City; her father is the go-to voice-over talent for blockbuster films. Hers is a world of private planes, chauffeurs, paparazzi and gossip columnists. When Cammi's mom gets cast in an American television show and the family moves to LA, things change, and quickly. Her mom's first role is playing a not-so-glamorous maid in a sitcom. Her dad tries to find work but dreams about returning to Mexico....

When Jayd starts dating a half-Jewish white boy, her ex-boyfriend KJ starts trouble, while her enemy Misty and an anti-black teacher make her life miserable, forcing her to rely on Mama's magic to get through another day at Drama High.