Sam Kean
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The periodic table of the elements is a crowning scientific achievement, but it's also a treasure trove of passion, adventure, obsession, and betrayal. These tales follow carbon, neon, silicon, gold, and all the elements in the table as they play out their parts in human history. The usual suspects are here, like Marie Curie (and her radioactive journey to the discovery of polonium and radium) and William Shockley (who is credited, not exactly justly,...
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"Science is a force for good in the world--at least usually. But sometimes, when obsession gets the better of scientists, they twist a noble pursuit into something sinister. Under this spell, knowledge isn't everything, it's the only thing--no matter the cost. Bestselling author Sam Kean tells the true story of what happens when unfettered ambition pushes otherwise rational men and women to cross the line in the name of science, trampling ethical...
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"The fascinating science and history of the air we breathe: It's invisible. It's ever-present. Without it, you would die in minutes. And it has an epic story to tell. In Caesar's Last Breath, ... bestselling author Sam Kean takes us on a journey through the periodic table, around the globe, and across time to tell the story of the air we breathe, which, it turns out, is also the story of earth and our existence on it. With every breath, you literally...
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A collection of the year's best science and nature writings, selected by New York Times bestselling author Sam Kean.
"This is one of the most exciting times in the history of science," Sam Kean proclaims in his introduction to The Best American Science and Nature Writing 2018. "Things aren't perfect by any means. But there are more scientists making more discoveries in more places about more things than ever before."
The...
"This is one of the most exciting times in the history of science," Sam Kean proclaims in his introduction to The Best American Science and Nature Writing 2018. "Things aren't perfect by any means. But there are more scientists making more discoveries in more places about more things than ever before."
The...
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A young readers edition of the New York Times bestseller The Disappearing Spoon, chronicling the extraordinary stories behind one of the greatest scientific tools in existence: the periodic table.
Why did Gandhi hate iodine (I, 53)? How did radium (Ra, 88) nearly ruin Marie Curie's reputation? And why did tellurium (Te, 52) lead to the most bizarre gold rush in history?
The periodic table is a crowning scientific achievement,...
Why did Gandhi hate iodine (I, 53)? How did radium (Ra, 88) nearly ruin Marie Curie's reputation? And why did tellurium (Te, 52) lead to the most bizarre gold rush in history?
The periodic table is a crowning scientific achievement,...
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The decoding of the human genome paved the way for Project ENCODE, designed to identify functional elements in the genome. Focus on examples that are central to human culture, such as language. Probe the foxp2 gene that appears to play a role in speech, together with other genes. Consider the role of mutations and nature's gene splicing in boosting our brain and cognitive abilities.
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Cover the "Manhattan Project" of DNA: the Human Genome Project to sequence all three billion base pairs of human genetic material. Two separate teams, led by Francis Collins and Craig Venter, competed bitterly to reach this costly goal, which required new technologies and controversial methods. Examine the politics and unexpected legacy of this effort, which was declared complete in 2003.
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Investigate the first precision technique for genetic engineering, CRISPR, heralded as holding the potential for science fiction-like manipulation of the human genome. Trace the history of CRISPR-based techniques from a coastal salt marsh, to the fight over patents. Consider the potential for abuse of this powerful tool.
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Where did humans originate? When did we first start wearing clothes? How did the agricultural revolution spread? Delve into historical questions that DNA has answered, involving figures such as King Tut, Genghis Khan, Thomas Jefferson, and King Richard III. Consider Abraham Lincoln to ask where we draw the line in reading genetic secrets from the past.
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Look at the genetic basis for certain diseases and how personalized genetic medicine might be customized to the hidden histories that each of us have written in our DNA. Discover what makes the challenges so daunting and focus in particular on the different mechanisms behind different cancers, and how genetics helps us disentangle the differences.
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Because DNA is only a blueprint, the discovery of its double helix structure was just the beginning. Trace the next big step: understanding how DNA synthesizes proteins through the intermediary of RNA. Here again, a dark horse researcher (Marshall Nirenberg) made the crucial breakthrough. Then see how DNA fingerprinting became possible in the 1980s.
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In the wake of the Human Genome Project, scientists were able to chart our shared heritage with a multitude of species. Most startling was evidence of breeding between modern humans and Neanderthals in the deep past, with a small percentage of Neanderthal DNA present in major human populations today. Peer into the human genome to read these and other clues about our multifaceted history.
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Join the quest to understand the molecular biology of the gene with the famous blender experiment, which showed that DNA, not proteins, transmit genetic information. Then look at five scientists who competed to solve the mystery of DNA's structure, including Rosalind Franklin and a team of rookie investigators who stumbled embarrassingly in their first attempt.
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Every cell in the human body has essentially the same DNA, yet cells behave very differently, partly due to epigenetics. In epigenetics, the DNA genetic sequence remains constant, but the activity of that sequence changes as genes get switched on and off. More surprising, epigenetics also explains how the inheritance of traits can be influenced by environmental factors.
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Enter the home stretch in the race to find the structure of DNA. With eminent chemist Linus Pauling leading the pack, longshots James Watson and Francis Crick got a key clue from rival investigator Rosalind Franklin (without her knowledge). Analyze the reasoning that led Watson and Crick to their 1953 breakthrough, and consider why Franklin didn't beat them to it.
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Investigate the curious career of microbes in our bodies, not just the ones that make us sick, but more crucially, those that get incorporated into our DNA, driving evolution in unpredictable ways. For instance, the placenta that makes most mammals distinct from egg-laying animals appears to be an adaptation derived from an invasive virus. Learn why 8% of our genome is viral in origin.
19) The violinist's thumb: and other lost tales of love, war, and genius, as written by our genetic code
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"In The Disappearing Spoon, bestselling author Sam Kean unlocked the mysteries of the periodic table. In THE VIOLINIST'S THUMB, he explores the wonders of the magical building block of life: DNA. There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans...
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Early studies of the human brain used a simple method: wait for misfortune to strike--strokes, seizures, infectious diseases, horrendous accidents--and see how victims coped. In many cases their survival was miraculous, if puzzling. Observers were amazed by the transformations that took place when different parts of the brain were destroyed, altering victims' personalities. Parents suddenly couldn't recognize their own children. Pillars of the community...